血清C反应蛋白、胰蛋白酶原-2、血小板活化因子在ERCP术后急性胰腺炎早期诊断中的临床意义

doi:10.3969/j.issn.1671-7171.2017.02.022

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Abstract 【Objective】To discuss clinical significance of serum CRP, trypsin -2 and PAF in early diagnosis of acute pancreatitis after ERCP. 【Methods】 A total of 108 cases underwent ERCP in the department of digestive medicine from Jan 2014 to Dec 2016 was selected as subjects. After ERCP, the patients were divided into pancreatitis group, high amylase group and control group according to the occurrence of acute pancreatitis. Amylase, CRP, trypsin -2 and PAF were detected before ERCP , 6h and 24h after ERCP . 【Results】 At 6h after ERCP, serum amylase and CRP levels of the pancreatitis group and the high amylase group increased significantly; at 24h after ERCP, serum amylase and CRP levels of the pancreatitis group continued to rise, and the high amylase group decreased, which were higher than those before ERCP,the differences were statistically significant(P＜0.05). At 6h and 24h after ERCP, serum amylase and CRP levels of the pancreatitis group were the highest, the next was the high amylase group, and the control group was the lowest, which showed significant difference in the three groups(P＜0.05). At 6h after ERCP, trypsin -2 and PAF levels of the pancreatitis group and the high amylase group increased, but decreased 24h after ERCP, which were higher than those before ERCP(P＜0.05). At 6h and 24h after ERCP, serum trypsin-2 and PAF levels of the pancreatitis group were the highest, the next was the high amylase group, and the control group was the lowest, which showed significant difference statistically(P＜0.01). 【Conclusion】 CRP, trypsin-2 and PAF levels increased in early stage after ERCP in patients with acute pancreatitis.CRP,trypsin-2 and PAF can be detected through clinical examination to determine whether patients are with acute pancreatitis,so as to prevent and deal with it in time.

Key words： C-Reactive Protein Trypsinogen Platelet Activating Factor Cholangiopancreatography, Endoscopic Retrograde/AE Pancreatitis/ET Acute Disease Early Diagnosis

Received: 05 December 2016

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	LIU Yu-qing
	LU Qi-ming

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LIU Yu-qing,LU Qi-ming. Clinical Significance of Serum CRP, Trypsin -2 and PAF in Early Diagnosis of Acute Pancreatitis after ERCP[J]. JOURNAL OF CLINICAL RESEARCH, 2017, 34(2): 276-278.

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http://www.jcr.net.cn/EN/10.3969/j.issn.1671-7171.2017.02.022 OR http://www.jcr.net.cn/EN/Y2017/V34/I2/276

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