|
|
Value of 18F-FDG PET/CT Imaging in the Evaluation of Metastasis or Recurrence of Cervical Cancer after Radical Operation |
WEI Jing; WANG Shu-zhong |
The first people's Hospital of HuaiAn, HuaiAn City, Jiangsu Province, 223300 |
|
|
Abstract 【Objective】To analyze the clinical value of 18F-deoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) in evaluating the metastasis or recurrence of cervical cancer after radical operation. 【Methods】Sixty patients with suspected recurrence or metastasis of cervical cancer after radical operation were studied. All patients had pathological diagnosis of cervical cancer. All underwent 18F-FDG PET/CT examinations and the results were compared with the results of pathology and follow-up. The application value of 18F-FDG PET/CT imaging in the diagnosis of postoperative metastasis and recurrence of cervical cancer was evaluated. 【Results】18F-FDG PET/CT imaging detected that metastasis or recurrence was positive in 47 cases and negative in 13 cases, 30 cases of which were tumor metastasis and 17 cases which were local recurrence after radical operation of cervical cancer. The diagnostic sensitivity, specificity and accuracy were 97.83%, 85.71% and 95.00%, respectively, and the positive and negative predictive values were 95.74% and 90.31% respectively. The consistency of 18F-FDG PET/CT with results of pathology and follow-up was higher (P=0.000). 【Conclusion】18F-FDG PET/CT imaging is of high value in the diagnosis of recurrence and metastasis after radical operation of cervical cancer; it has high sensitivity, specificity and accuracy, which can provide effective reference for clinical treatment of cervical cancer.
|
Received: 07 November 2016
|
|
|
|
|
[1] 唐莉, 钟文彬, 陈亮,等. TCT联合高危型HPV检测在宫颈病变筛查中的应用价值[J].医学临床研究, 2016, 33(7):1417-1418. [2] 李欢欢,游金辉,谌伦华,等.18F-FDG PET/CT在宫颈癌诊治中的应用[J].中华核医学与分子影像杂志,2014,34(6):526-528. [3] 陈丹丹,吴湖炳,王全师,等.18F-FDG PET/CT在复发宫颈癌疗效评价及预后预测中的价值[J].中华核医学与分子影像杂志,2015,35(3):168-172. [4] 赵妍,赵新明,张召奇,等.氟代脱氧葡萄糖PET/CT对宫颈癌复发和转移的诊断价值[J].中国全科医学,2013,16(29):3475-3477,3482. [5] 张艳,毕崇萍,杜聚,等.18F-FDG PET/CT在宫颈癌诊断及分期中的临床价值[J].现代生物医学进展,2016,16(6):1061-1063. [6] 王胜军,陆宏军,杨卫东,等.18F-FDG PET/CT代谢体积与病理体积对比确定宫颈癌最大标准摄取值的最佳百分阈值[J].解放军医学杂志,2013,38(8):653-656. [7] 于珊珊,刘晓龙.18F-FDG PET/CT在宫颈癌的应用价值[J].医学影像学杂志,2015,25(10):1882-1885. [8] 陈峰,林天增,郁春景,等.18F-FDG PET/CT显像在治疗后宫颈癌评估中的价值[J].中华核医学与分子影像杂志,2015,35(3):164-167. |
|
|
|