|
|
Influencing Factors of Poorly Expected Effect of Calcium Supplementary Treatment in Patients with Maintenance Hemodialysis-induced Osteoporosis |
DING Zheng; ZENG Guang |
Department of Orthopedics, Shanghai Tongreng Hospital,Shanghai 200336 |
|
|
Abstract 【Objective】To investigate the influencing factors of poor effect of calcium supplementary treatment in patients with maintenance hemodialysis (MHD)-induced osteoporosis. 【Methods】A total of 136 patients with MHD-induced osteoporosis were analyzed retrospectively. According to the effect of calcium supplementary treatment, they were divided into the excellent group (n=84) and the poor group (n=52). General information was compared between the two groups. Analysis was performed to analyze the related factors influencing poor effect of calcium supplementary treatment in patients with MHD-induced osteoporosis. 【Results】 There were no significant differences in BMI levels, hyperlipidemia and hypertension status, and bone mineral density T value before calcium supplement between the two groups (P>0.05). The proportions of age, gender (female), diabetes rate, MHD time, and unhealthy living habits (smoking, drinking, staying up overnight) during the treatment in the excellent group were significantly lower than those in the poor group, while daily walking distance and time was significantly more than that of the poor group (P<0.05). The multivariate logistic regression analysis showed that age, gender, diabetes, MHD time, daily walking habits, smoking, drinking, and staying up late were the related factors influencing the effect of calcium supplementary treatment in patients with MHD-induced osteoporosis (P<0.05). 【Conclusion】Age, being female, diabetes, MHD time, smoking, drinking and staying up late during the treatment are the independent risk factors influencing the effect of calcium supplementary treatment in patients with MHD-induced osteoporosis, while daily exercise is the protective factor.
|
Received: 16 August 2016
|
|
|
|
|
[1] 王刚,姜群,张东亮,等.维持性血液透析患者骨质疏松患病情况及其危险因素分析[J].临床和实验医学杂志,2013,12(16):1277-1279. [2] 谌贻璞.肾内科学[M].第2版.北京:人民卫生出版社,2015:266-279. [3] 胥少汀.实用骨科学[M].第4版.北京:人民军医出版社,2012:315-317. [4] 张寒.慢性肾脏病患者血管钙化与骨质疏松共同发生机制的研究进展[J].医学综述,2012,18(18):2991-2994. [5] 霍亚南,郭莉,吴秀春,等.老年男性糖尿病合并骨质疏松相关危险因素分析[J].中国老年学杂志,2011,31(11):2121-2122. [6] 王小华,殷士良,王彩云,等.绝经后2型糖尿病女性雌激素水平与骨质疏松的相关性研究[J].医学临床研究,2014,31(8):1561-1563. [7] 金铃,刘辉文,谭万寿,等.2260例成年男性骨质疏松症危险因素分析[J].医学临床研究,2014,31(2):241-243. [8] 尹嘉晶,彭永德.糖尿病与骨质疏松[J].中华内分泌代谢杂志,2014,30(5):449-452. [9] 张新,黄静,李新,等.运动强度及透析龄等相关因素对血液透析患者骨密度的影响[J].中国血液净化,2014,13(4):306-310. [10] 张宇梅,耿磊,张凌,等.维持性血液透析患者骨密度的测定结果与分析[J].中国血液净化,2014,13(3):137-139. [11] 王小华,王宇强,陈长香,等.吸烟、饮酒、喝绿茶等生活习惯对老年人骨质疏松的影响[J].中国骨质疏松杂志,2015,21(10):1187-1190,1200. |
|
|
|