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| Clinical Efficacy and Safety of Gestrinone and Levonorgestrel-Releasing Intrauterine System (LNG-IUS) in Treatment of Adenomyosis |
| LI Xu-qing, TAO li-na, REN Hong-ye |
| Women Health Care, Maternal and child health care family planning service center of Xigang,Dalian 116011 |
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Abstract 【Objective】To discuss the clinical efficacy and safety of gestrinone and levonorgestrel-releasing intrauterine system (LNG-IUS) in the treatment of adenomyosis. 【Methods】One hundred and sixty-eight cases of adenomyosis in our hospital from February 2014 to March 2016 were selected and divided into the observation group and the control group by random number table method. The observation group was treated with LNG-IUS, while the control group with gestrinone. The degree of dysmenorrhea, uterine volume, endometrial thickness, menstrual volume, hemoglobin levels and adverse reactions were compared between the two groups before and after treatment.【Results】 Compared with the conditions before treatment, dysmenorrhea and menorrhagia of the two groups of patients after treatment were significantly relieved. Hemoglobin levels were significantly increased, and the dysmenorrhea, menorrhagia and anemia symptoms of the observation group were improved (P<0.05); Compared with the control group before treatment, the endometrial thickness and uterine volume of the observation group after treatment were significantly reduced (P<0.05); there was no significant difference in endometrial thickness and uterine volume in the control group before and after treatment (P>0.05); Compared with the control group, the incidence of adverse reactions was obviously lower in the observation group (P<0.05).【Conclusion】The effect of LNG-IUS in treatment of adenomyosis is significantly better than that of gestrinone, and it is safe and worthy of clinical application.
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Received: 08 August 2016
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2017, Vol. 34 
