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| Study of Acute Kidney Injury and Related Risk Factors on Children with Acyanotic Congenital Heart Disease after CPB Cardiac Surgery |
| WANG Lei, TONG Rui |
| Department of cardiothoracic surgery,Xuzhou Children's Hospital,Xuzhou,Jiangsu 221000,China |
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Abstract 【Objective】To study the incidence of acute kidney injury (AKI) and related risk factors on children with acyanotic congenital heart disease after cardiopulmonary bypass (CPB) cardiac surgery.【Methods】One hundred and twenty-eight patients with CPB surgery in our hospital from October 2013 to October 2015 were selected as the subjects.They were divided into AKI group and non AKI group on the basis with AKI complicated or not after treatment, with 25 cases in AKI group and 103 in non AKI group . The clinical data of the two groups were compared, and the related factors of AKI were determined by single factor analysis. Multivariate Logistic regression analysis was used to determine the independent factors.【Results】Single factor analysis showed that age, body mass, accompanied with pneumonia, heart failure, serum creatinine, uric acid, operative time, aortic clamping time, postoperative blood transfusion volume, mechanical ventilation time, postoperative hypotension, whole blood activated clotting time and hospitalization time were all of the related factors on children with acyanotic congenital heart disease after cardiopulmonary bypass (CPB) cardiac surgery complicated with AKI. Multivariate Logistic regression analysis showed that age, body mass, accompanying pneumonia, concomitant heart failure, operation time, aortic occlusion time were independent factors.【Conclusion】 The complicated AKI after cardiac surgery on children with acyanotic congenital heart disease is a reversible injury at early stage, Prompt treatment is effective on the prognosis of diseased children.
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2017, Vol. 34 
