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| Observation of Kidney Injuries after Ureterscopy Lithotripsy |
| YU Jia-shun, LIU Ding-yi, WANG Jian,et al |
| Department of Urology, Shanghai Pudong New Area Punan Hospital, Shanghai 200125, China |
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Abstract 【Objective】To discuss the injury and recovery of the glomeruli and renal tubule after ureterscopy lithotripsy(URSL). 【Methods】We performed URSL (holmium laser lithotripsy) for 215 patients with ureter stones. The study subjects were divided into the upper ureteral calculi (Group A) and distal ureteral calculi (Group B) according to the position of the stones, as well as the ＜30 min (Group C) and ≥30 min (Group D) according to operation time. By assessing the patients' indicators of urinary microprotein (mALB), N-acetyl-β-glucosaminidase (NAG), retinol binding protein (RBP) before operation and 24 hours, one week, one month, two months after operation, we evaluated the injuries of the glomeruli and renal tubule caused by URSL surgery, and investigated the effects of stone position and operation period on the injury and the injury recovery progress. 【Results】The patients' mALB, NAG, and RBP after operation were significantly above those before the operation (P＜0.01) but then gradually declined after one to two months. The higher the position of the stone and the longer the operation time, the more dramatic the increase of NAG was after operation (P＜0.05). 【Conclusion】Ureterscopy lithotripsy causes injury to both the glomeruli and renal tubule. The injury of renal tubule was more serious when there was a higher stone position and longer operation time. The injury was self-restoring after one to two months after operation.
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Received: 04 November 2016
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2017, Vol. 34 
