高通量血液透析对慢性肾衰竭尿毒症患者肺总量、免疫球蛋白水平及生活质量的影响

doi:10.3969/j.issn.1671-7171.2017.01.003

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Abstract 【Objective】To investigate the effects of high flux hemodialysis on TLC, immunoglobulin level and QOL in the treatment of patients with chronic renal failure uremia . 【Methods】A total of 100 patients with chronic renal failure uremia from December 2012 to December 2015 in our hospital were collected and randomly divided into experiment group and control group with 50 cases in each group. Patients in the control group were treated by hemodialysis filtration treatment, three times a week; patients in the experiment group were treated by high flux hemodialysis therapy, three times a week, 28 d as a course of treatment. The TLC, immunoglobulin level and QOL of the two groups were compared before and after treatment . 【Results】 At the end of the treatment, the effective rate of the experiment group (96.0%,48/50) was higher than that of the control group (86.0%,43/50), the difference was statistical significance (P<0.05); Compared with before treatment, the serum creatinine level of the two groups were decreased , immunoglobulin IgA, IgM and IgG levels were increased, lung function TLC level increased , quality of life index (QOL) score increased (P<0.05), the difference was statistical significance . Compared with control group, the serum creatinine level of the experiment group was lower , immunoglobulin IgA, IgM and IgG levels were higher,TLC lung function level was higher, quality of life index (QOL) scored was higher (P<0.05), the difference was statistical significance ; Compared with the control group, the clinical complications rate of the experiment group was lower, the difference was statistical significance(P<0.05). 【Conclusion】Compared with hemodialysis, high flux hemodialysis treatment can better improve the patient's lung function, enhance immune function, improve the patient's QOL, which is worthy of clinical application.

Key words： Kidney Failure, Chronic Renal Dialysis Uremia Total Lung Capacity Immunoglobulins Quality of Life

Received: 14 March 2016

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R692.5

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http://www.jcr.net.cn/EN/10.3969/j.issn.1671-7171.2017.01.003 OR http://www.jcr.net.cn/EN/Y2017/V34/I1/8

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