[1] Xiao X, Wang W, Wang Z,et al.The role of chemotherapy for metastatic, relapsed and refractory osteosarcoma[J].Paediatr Drugs,2014,16(6): 503-512. [2] Li Z, Yu X, Shen J,et al. Long non-coding RNAs: emerging players in osteosarcoma[J].Tumour Biol,2016,37(3): 2811-2816. [3] Huynh NP,Anderson BA,Guilak F, et al.Emerging roles for long noncoding RNAs in skeletal biology and disease[J].Connect Tissue Res,2016,13(2): 1-26. [4] Panzitt K, Tschernatsch MM,Guelly C,et al.Characterization of HULC, a novel gene with striking up-regulation in hepatocellular carcinoma, as noncoding RNA[J].Gastroenterology,2007,132(1): 330-342. [5] Sun XH, Yang LB, Geng XL,et al.Increased expression of lncRNA HULC indicates a poor prognosis and promotes cell metastasis in osteosarcoma[J].Int J Clin Exp Pathol,2015,8(3): 2994-3000. [6] Uzan VR,Lengert Av,Boldrini E, et al.High Expression of HULC Is Associated with Poor Prognosis in Osteosarcoma Patients[J].PLoS One,2016,11(6): 156-164. [7] Ulaner GA, Yang Y,Hu JF,et al.CTCF binding at the insulin-like growth factor-II (IGF2)/H19 imprinting control region is insufficient to regulate IGF2/H19 expression in human tissues[J].Endocrinology,2003,144(10): 4420-4426. [8] Ulaner GA,Vu TH,Li T, et al.Loss of imprinting of IGF2 and H19 in osteosarcoma is accompanied by reciprocal methylation changes of a CTCF-binding site[J].Hum Mol Genet,2003,12(5): 535-549. [9] Jiang X, YanY,Hu M,et al.Increased level of H19 long noncoding RNA promotes invasion, angiogenesis, and stemness of glioblastoma cells[J].J Neurosurg,2016,124(1): 129-136. [10] Chan LH, Wang W,Yeung W,et al.Hedgehog signaling induces osteosarcoma development through Yap1 and H19 overexpression[J].Oncogene,2014,33(40): 4857-4866. [11] Li M,Chen H,Zhao Y,et al. H19 Functions as a ceRNA in Promoting Metastasis Through Decreasing miR-200s Activity in Osteosarcoma[J].DNA Cell Biol,2016,35(5):235-240. [12] He P, Zhang Z,Huang G,et al.miR-141 modulates osteoblastic cell proliferation by regulating the target gene of lncRNA H19 and lncRNA H19-derived miR-675[J].PLoS One,2016,8(4): 1780-1788. [13] Zhu L, Xu PC. Downregulated LncRNA-ANCR promotes osteoblast differentiation by targeting EZH2 and regulating Runx2 expression.[1090-2104 (Electronic)]. [14] Min L, Hong S,Duan H,et al.Antidifferentiation Noncoding RNA Regulates the Proliferation of Osteosarcoma Cells[J].Cancer Biother Radiopharm,2016,31(2): 52-57. [15] DongY,Liang G,Yuan B, et al.MALAT1 promotes the proliferation and metastasis of osteosarcoma cells by activating the PI3K/Akt pathway[J].Tumour Biol,2015,36(3): 1477-1486. [16] Fang D, Yang H,Lin J,et al.17beta-estradiol regulates cell proliferation, colony formation, migration, invasion and promotes apoptosis by upregulating miR-9 and thus degrades MALAT-1 in osteosarcoma cell MG-63 in an estrogen receptor-independent manner[J].Biochem Biophys Res Commun,2015,457(4): 500-506. [17] Taniguchi M, Fujiwara K,Nakai Y,et al.Inhibition of malignant phenotypes of human osteosarcoma cells by a gene silencer, a pyrrole-imidazole polyamide, which targets an E-box motif[J].FEBS Open Biol,2014,4:328-334. [18] Cai X,Liu Y,Yang W, et al.Long noncoding RNA MALAT1 as a potential therapeutic target in osteosarcoma[J].J Orthop Res,2016,34(6): 932-941. [19] Han Y,Liu Y,Gui Y, et al. Long intergenic non-coding RNA TUG1 is overexpressed in urothelial carcinoma of the bladder[J].J Surg Oncol,2013.107(5): 555-559. [20] Zhang EB, Yin DD,Sun M,et al.P53-regulated long non-coding RNA TUG1 affects cell proliferation in human non-small cell lung cancer, partly through epigenetically regulating HOXB7 expression[J].Cell Death Dis,2014,5(10): 1243-1252. [21] Huang MD, Chen WM,Qi FZ,et al.Long non-coding RNA TUG1 is up-regulated in hepatocellular carcinoma and promotes cell growth and apoptosis by epigenetically silencing of KLF2[J].Mol Cancer,2015,14: 165-173. [22] Zhang Q, Geng PL, Yin P, et al.Down-regulation of long non-coding RNA TUG1 inhibits osteosarcoma cell proliferation and promotes apoptosis[J].Asian Pac J Cancer Prev,2013,14(4): 2311-2315. [23] Ma B, Li M,Zhang L,et al.Upregulation of long non-coding RNA TUG1 correlates with poor prognosis and disease status in osteosarcoma[J].Tumour Biol,2016,37(4): 4445-4455. [24] Li JP,Liu LH,Li J, et al.Microarray expression profile of long noncoding RNAs in human osteosarcoma[J].Biochem Biophys Res Commun,2013,433(2): 200-206. [25] Sun J,Wang X,Fu C, et al.Long noncoding RNA FGFR3-AS1 promotes osteosarcoma growth through regulating its natural antisense transcript FGFR3[J].Mol Biol Rep,2016,43(5): 427-436. [26] Zhou X, Chen J, Tang W,et al.The molecular mechanism of HOTAIR in tumorigenesis, metastasis, and drug resistance[J].Acta Biochim Biophys Sin,2014,46(12): 1011-1015. [27] Wang B,Su Y,Yang Q, et al.Overexpression of Long Non-Coding RNA HOTAIR Promotes Tumor Growth and Metastasis in Human Osteosarcoma[J].Mol Cells,2015,38(5): 432-440. [28] Zhang J,Zhu X,Li H, et al.Piperine inhibits proliferation of human osteosarcoma cells via G2/M phase arrest and metastasis by suppressing MMP-2/-9 expression[J].Int Immunopharmacol,2015,24(1) 50-58. [29] Zhou Q, Chen F,Fei Z, et al.Genetic variants of lncRNA HOTAIR contribute to the risk of osteosarcoma[J].Oncotarget,2016,7(15): 19928-19934. [30] Li F, Cao L,Hang D,et al.Long non-coding RNA HOTTIP is up-regulated and associated with poor prognosis in patients with osteosarcoma[J].Int J Clin Exp Pathol,2015,8(9): 11414-11420. [31] Li Z, Zhao L, Wang Q,et al.Overexpression of long non-coding RNA HOTTIP increases chemoresistance of osteosarcoma cell by activating the Wnt/beta-catenin pathway[J].Am J Transl Res,2016,8(5): 2385-2393. [32] Zhang CL,Zhu KP,Shen GQ, et al.A long non-coding RNA contributes to doxorubicin resistance of osteosarcoma[J].Tumour Biol,2016,37(2): 2737-2748. [33] Wang XS, Zhang Z,Wang HC, et al.Rapid identification of UCA1 as a very sensitive and specific unique marker for human bladder carcinoma[J].Clin Cancer Res,2006,12(16): 4851-4858. [34] Li W, Xie P, Ruan WH,et al.Overexpression of lncRNA UCA1 promotes osteosarcoma progression and correlates with poor prognosis[J].J Bone Oncol,2016,5(2): 80-85. [35] Ding YC,Yu W,Ma C, et al.Expression of long non-coding RNA LOC285194 and its prognostic significance in human pancreatic ductal adenocarcinoma[J].Int J Clin Exp Pathol,2014,7(11): 8065-8070. [36] Pasic I, Shlien A, Durbin AD, et al.Recurrent focal copy-number changes and loss of heterozygosity implicate two noncoding RNAs and one tumor suppressor gene at chromosome 3q13.31 in osteosarcoma[J].Cancer Res,2010,70(1): 160-171. [37] Liu Q,Huang J,Zhou N, et al.LncRNA loc285194 is a p53-regulated tumor suppressor[J].Nucleic Acids Res,2013,41(9): 4976-4987. [38] Tian ZZ, Guo XJ, Zhao YM, et al.Decreased expression of long non-coding RNA MEG3 acts as a potential predictor biomarker in progression and poor prognosis of osteosarcoma[J].Int J Clin Exp Pathol,2015,8(11): 15138-15142. [39] Cong M, Li J,Jing R, et al.Long non-coding RNA tumor suppressor candidate 7 functions as a tumor suppressor and inhibits proliferation in osteosarcoma[J].Tumour Biol,2016,23(4):171-18314. |