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| SOX Neoadjuvant Chemotherapy on the Surgical Removal and Postoperative Complications of Gastric Cancer Surgery in Advanced Stage Patients |
| SONG Hua-yong, ZHANG Fan, MA Lei |
| The First Affiliated Hospital of Henan University,Kaifeng Henan 475001 |
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Abstract 【Objective】To explore the effects of the SOX neoadjuvant chemotherapy on the surgical clearance and complications in patients with advanced gastric cancer stage Ⅱ~Ⅲ and undergoing gastric cancer surgery. 【Methods】One hundred and fifty cases of advanced gastric cancer were admitted into the study. The study subjects were randomly divided into the observation group (54 cases) and control group (51 cases). The control group was only given the tradition gastric cancer surgery. The observation group underwent SOX neoadjuvant chemotherapy before undergoing traditional gastric cancer surgery. After the procedure, the postoperative clearance and complications were compared between the two groups. 【Results】The observation group, through TNM staging, showed that tumor stage was significantly lower (P<0.05). The observation group's surgical removal rate (90.74%) was significantly higher than that of the control group (P<0.05). The operative time (167.92 min ± 46.62 min) and intraoperative blood loss (239.45 mL±32.96 mL) were significantly higher than in the control group (P<0.05). The postoperative complication rate was not significantly different between the two groups (P>0.05). 【Conclusion】Application of SOX neoadjuvant chemotherapy in advanced gastric cancer patients undergoing gastric cancer surgery reduces the tumor stage, increases the surgical removal, and does not increase the risk of postoperative complications.
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Received: 15 May 2016
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2016, Vol. 33 
