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| Analysis of Related Factors of Hemorrhage Events in Patients with Acute Coronary Syndrome |
| The People's Hospital of Chongqing Shapingba District, Chongqing 400030 |
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Abstract 【Objective】To investigate the related factors of hemorrhage events in patients with acute coronary syndrome (ACS).【Methods】 Seven hundred and fiftythree cases diagnosed as ACS in our hospital from May 2005 to May 2015 were selected, and 12 of them complicated with hemorrhage were regarded as hemorrhage group according to the criterion of hemorrhagic events，while 48 of them without hemorrhage were selected by stratified random sampling method as no hemorrhage group. The clinical features, complications, treatment and drug application of the two groups were compared.【Results】The complicated hemorrhage rate of this research was 1.6%（12/753）. The patients' age in the hemorrhage group were older ，and their hospitalstay time were longer than those in the no hemorrhage group (P＜0.05). Additionally, patients complicated with cardiac insufficiency, renal insufficiency and past history of hemorrhage got higher rate of hemorrhage (P＜0.05). ACS patients treated with clopidogrel and platelet membrane proteinⅡb/Ⅲa（GPⅡb/Ⅲa）receptor antagonist or underwent PCI and (or) CABG in superior hospitals got a higher rate of hemorrhage (P＜0.05). 【Conclusion】 ACS patients with senior age, combined cardiac insufficiency, renal insufficiency, previous history of bleeding, once underwent PCI and / or CABG, or treated with clopidogrel or GP Ⅱb/ Ⅲa receptor antagonists are more vulnerable to hemorrhage.
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Received: 19 February 2016
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2016, Vol. 33 
