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| Correlative Analysis of Urinary Albumin Excretion with Retinopathy in Patients with Type 2 Diabetes Mellitus |
| Department of Endocrinology, Yibin Second People's Hospital, Yibin, 644000 ,Sichuan,China |
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Abstract 【Objective】 To analyze the relationship between urinary albumin excretion and diabetic retinopathy in type 2 diabetics mellitus. 【Methods】 Two hundred and sixty patients with type 2 diabetics mellitus were divided into normal albuminuria group(NA,n=41, 24hurinary albumin≤30mg), microalbuminuria group (MAU,n=118,30mg＜24hurinary albumin＜300mg) and macroalbuminuria group(CAU,n=101, 24hurinary albumin≥300mg). All the patients were measured in terms of 24hurinary albumin and examined by digital retinal photographs, thus the relationship between urinary albumin excretion and diabetic retinopathy in type 2 diabetics can be analyzed. 【Results】 The non proliferative diabetic retinopathy (NPDR) detection rate in the NA group was 9.8%, and the detection rate of proliferative diabetic retinopathy (PDR) was 4.8%; The detection rate of NPDR in the MAU group was 43.2%, and the detection rate of PDR was 16.1%; The detection rate of NPDR in the CAU group was 42.6%, and the detection rate of PDR was 34.7%; There were significant differences in the detection rates of NPDR and PDR in each group (P<0.05); Correlation analysis showed that urinary albumin excretion rate was positively correlated with the rate of DR in T2DM patients (P<0.05).【Conclusion】 The urinary albumin excretion rate of T2DM patients is significantly correlated with the occurrence of DR. The above factors may have a common pathophysiological basis.
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Received: 24 February 2016
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2016, Vol. 33 
