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| Risk Factors of Infants Group B Streptococcus (GBS) for Septicemia and its Perinatal Clinical Features |
| Pediatrics, Changsha Fourth Hospital, Changsha , Hunan 410006 |
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Abstract 【Objective】To investigate the risk factors of infants Group B streptococcus (GBS) for septicemia and its perinatal clinical features.【Methods】The clinical data of 34 children with GBS in our hospital from May 2013 to May 2015 were analyzed retrospectively and compared with that of 30 cases of children with non GBS gram positive bacterial sepsis at the same period.【Results】The first symptom of early onset GBS sepsis occurred mainly in respiratory systems, while that of late onset GBS sepsis were with high fever or low body temperature. The difference of symptoms of lateonset GBS sepsis and lateonset non GBS sepsis like convulsions and shortness of breath had statistical significance (P<0.05). Penicillin was considered as the preferred drug for GBS treatment. GBS is highly sensitive to penicillin, ampicillin, ceftriaxone, meropenem and vancomycin, thus duplex treatment is usually used for the therapy.【Conclusion】 Early onset GBS sepsis invaded early with dangerous symptoms had high death rate. Late onset sepsis conceals at early stage with less specificity and many complications , which is easy to cause meningitis. For pregnant women with 32~37 weeks of gestation, the bacteria culture of rectum and vagina GBS should be carried out in advance. The use of antibiotics for prevention of suspected GBS sepsis in children can effectively reduce the infection rate of GBS sepsis.
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Received: 26 January 2016
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2016, Vol. 33 
