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| Effects of Kang Fu Yan Capsule Combined with Dan Hong Injection on Inflammatory Factors in Patients with Chronic Pelvic Inflammatory Disease |
| Department of Obstetrics and Gynecology, Port Hospital of Hebei Port Group Co. Ltd. Qinhuangdao, Hebei 066000 |
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Abstract 【Objective】To study the effect of Kang Fu Yan capsule combined with Dan Hong Injection on inflammatory factors in patients with chronic pelvic inflammatory disease. 【Methods】The 160 cases of chronic pelvic inflammatory disease were randomly divided into two groups with 80 cases in each group. The control group received conventional western medicine treatment with the plus Kang Fu Yan capsule, (3 capsulesper time with twice a day for 8 days; another course was given after a resting period of 10 days). The observation group, upon the basis of the control group, also used an intravenous 20 ml Dan Hong injection +500 ml 5% glucose injection daily for 8 days, and after a resting period of 10 days, another course of treatment was given. Before and after treatment, by enzyme linked immunoassay, the detection of C reactive protein (CRP), tumor necrosis factor (TNF alpha), proinflammatory cytokines IL6, and antiinflammatory inflammatory cytokine IL4 levels were all detected and analyzed. 【Results】After two courses of treatment, the overall curative effect of observation group and the control group were 96.3% (77/80) and 85% (68/80), respectively. The former was better than the latter (χ2=12.335,P<0.05). After treatment, the two groups' TCM syndrome integrals and local signs improved, and the observation group was better than the control group (P<0.05). TNF, CRP, and IL6 factors were significantly lower than before treatment, whereas IL4 increased (P<0.05). The observation group was significantly higher than the control group (P<0.05). 【Conclusion】Kang Fu Yan capsule combined with Dan Hong injection can give full treatment to the antiinflammatory and invigorate the circulation of blood, regulate the level of inflammatory factor, balance proinflammatory cytokines and antiinflammatory cytokines levels, and effectively control chronic pelvic inflammation levels.
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Received: 01 December 2015
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2016, Vol. 33 
