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Abstract 【Objective】Comparative analysis of the effects of sevoflurane and ketamine anesthesia on pediatric tonsillectomy patients' induction and restlessness. This will provide the basis for clinical anesthesia medication. 【Methods】120 cases of children who received treatment for tonsillectomy in our hospital were randomly divided into a sevoflurane group（n=60）and a ketamine group（n=60）. After induction of anesthesia by phenobarbital and atropine, children received sevoflurane and ketamine, respectively . Anesthesia induction and restlessness situation were compared between the two groups. 【Results】The patient groups were able to successfully carry out surgery, and anesthetic effects are good. There were no serious accidents. However, children in the sevoflurane group had shorter operative times, extubation times, and recovery times than children in the ketamine; the difference was statistically significant (P<0.05). The incidence of children with bronchospasm and SpO2 instability were significantly lower in the sevoflurane than in the ketamine group (P<0.05). Before extubation, MAP and HR of the two groups had no significant difference (P>0.05). 5min after extubation, the number of children with HR was significantly higher in the sevoflurane group than in the ketamine group (P<0.05). After extubation, MAP in the sevoflurane group was significantly higher than in the ketamine group (P<0.05), but showed no significant difference later (P>0.05). Agitation incidence was 15.00% in the sevoflurane group and 63.33% in the ketamine group; the difference was statistically significant (P<0.05). This shows that the agitation score of the sevoflurane group was significantly lower than that of the ketamine group. The difference was statistically significant (P<0.05). 【Conclusion】Sevoflurane in children can cause a rapid heart rate and an increase in mean arterial pressure, but also allows for a quicker recovery compared to ketamine. However, ketamine anesthesia is more stable than sevoflurane. It allows for rapid recovery after surgery, a short anesthesia time, smooth hemodynamics, low incidence of side effects, few cases of restlessness. Ketamine is more suitable for children.
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Received: 06 November 2015
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2016, Vol. 33 
