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| Relationship Among Serum Uric Acid, Hypertension, and Prehypertension in MiddleAged People |
| Department of Cardiovascular Medicine, the Fourth Affiliated Hospital of China Medical Univercity, Shenyang, Liaoning 110032, China |
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Abstract 【Objective】 To study the relationship among serum uric acid, hypertension, and prehypertension in middleaged people. 【Methods】The 1,613 community residents aged 35~64 years who lived in Shenyang city were investigated. The associations among uric acid, hypertension, and prehypertension were analyzed though questionnaire survey, physical examination and biochemical detection. 【Results】 Means of uric acid levels were (317.32±81.25) μmol/L, (292.35±73.21) μmol/L, and (271.76±63.03) μmol/L in hypertensives, prehypertensives and normotensives respectively, with significant differences among the three groups (P<0.05). The mean level of systolic/diastolic blood pressures were (121.04±17.54)/(73.08±10.63)mmHg, (123.76±19.81)/(75.67±11.75)mmHg, (123.91±18.69)/(75.23±10.61)mmHg, and (131.08±19.54) /(80.02±11.19) mmHg for these with uric acid level in the first, second, third, and fourth quartiles. Adjusted odd ratios of hypertension and prehypertension in quartile 4 of uric acid were 2.31 (95%CI:1.51~3.54, P<0.01) and 1.52 (95%CI:1.03~2.22,P<0.01), with quartile 1 as a reference. 【Conclusion】 Serum uric acid level is associated with both hypertension and prehypertension in middleaged people. Therefore serum uric acid monitoring should be paid attention to.
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Received: 15 June 2015
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2015, Vol. 32 
