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| Efficacy of Oxycodone on Treatment of Intestinal Angina By Fibercolonscopy |
| Department of Anesthesiology ,Yue Bei People’s Hospital, Shaoguan, Guangdong, 512026 |
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Abstract 【Objective】To observe the effect of oxycodone injection on the analgesic effect and adverse reaction of outpatients underwent painless fibrecolonoscopy.【Methods】The 120 cases of painless colonoscopy were randomly divided into oxycodone group (Group O) and fentanyl group (Group F). The two groups were treated by intravenous anesthesia with oxycodone combined with propofol and fentanyl combined with propofol respectively. Elements like Preinduction of anesthesia (T0), pre start to check (T1), at the beginning of check (T2), through the hepatic flexure (T3), colonoscopy quit(T4)，recovery time(T5), five time points mean arterial pressure (MAP), heart rate (HR), arterial oxygen saturation (SpO2), respiratory rate (RR); the incidence of nausea and vomiting, dizziness, colic and other adverse reactions in the two groups of patients were compared with, and the duration of waking time and the time away from hospital were recorded and checked; The total amount of propofol and the incidence of adverse reactions such as nausea, vomiting, dizziness and colic in the two groups were detected.【Results】All patients were successfully completed colonoscopy. AT time points of T1 and T2, HR, SpO2 and RR in the Group F was significantly lower than those in the Group O (P<0.05). There was no significant difference between the two groups in the examination time, waking time, the time away from the hospital and the total amount of propofol. The probability of postoperative angina occurred in the Group O was obviously less than that of the Group F (P<0.05).【Conclusion】Propofol combined with oxycodone or with fentanyl for painless fibrecolonoscopy are safe and effective, but oxycodone is better with curing intestinal angina and has smaller effect on respiratory, circulatory system , which is more suitable for anesthesia in fibrecolonoscopy.
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Received: 26 October 2015
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| [1] |
. [J]. JOURNAL OF CLINICAL RESEARCH, 2015, 32(1): 142-143,144. |
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2015, Vol. 32 
