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Abstract [Objective]To evaluate the therapeutic effect of local immune regulation on subacute thyroiditis pa‐tients (SAT ) with nodules .[Methods]A total of 112 nodular SAT patients were randomly divided into two groups .The control group received an oral dose of prednisone while the observation group had an intra‐thyroid nodule injection of triamcinolone acetonide . The effectiveness and recurrence rate were compared between two groups .And the changes of clinical efficacies and indicators were observed .[Results]The withdrawal time of local pain symptoms was significantly shorter in observation group than that in control group(7 .3 ± 2 .7 vs 21 .1 ± 5 .2 days ,P<0 .01) .The same results were observed for thyroid nodule disappearing time (9 .7 ± 3 .4 vs 33 .5 ± 4 .9 days ,P<0 .01) .The effectiveness after 6‐month treatment were 88 .14% (52/59)in observation group versus 47 .17% (25/53) in control group .During a follow‐up period of 12 months ,the recurrence rate was significantly lower in observation group than that in control group [15 .4% (8/52) vs 28 .0% (7/25) ,P<0 .01] .[Conclusion]For nodular SAT patients ,local immune treatment via an intra‐thyroid nodule injection of triamcinolone acetonide is superior to an oral dose of prednisone .
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2015, Vol. 32 
