|
Abstract [Objective] To observe the clinical efficacies of leuprorelin acetate microspheres for uterine ade‐nomyosis with infertility .[Methods] A total of 60 infertile patients with uterine adenomyosis (observation group) undergoing in vitro fertilization embryo transplant (IVF‐ET) ovum induction after using leuprorelin ac‐etate microspheres were studied retrospectively .Another 60 infertile patients with tubal factors were enrolled as control group .The volumes of uterus and outcomes of IVF‐ET were compared between two groups .[Re‐sults] ① Volume of uterus :In observation group after 2~6 courses of therapy (3 .75 mg/28 days) ,the mean uterine volume shrank from (178 ± 75) to (85 ± 66) cm3 ( P <0 .05);② Outcome of IVF‐ET :The rate of embryo implantation ,clinical pregnancy and abortion between observation group (38 .8% ,53 .5% ,4 .3% ) and control group (35 .3% ,52 .8% ,3 .6% ) had no significant difference ( P > 0 .05);③ In observation group ,the rate of fertilization ,two pronuclear and superior embryo in patients with successful pregnancy (76 .1% ,67 .8% ,63 .4% ) after IVF‐ET were higher than those with failed pregnancy (61 .4% ,60 .8% , 50 .5% ) .[Conclusion] Leuprorelin acetate microspheres may shrink the volume of uterine adenomyosis and improve the outcomes of pregnancy in patients undergoing IVF‐ET .
|
|
|
|
|
|
2015, Vol. 32 
