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Abstract [Objective]To explore the level of high‐sensitivity C‐reactive protein(hs‐CRP) in hydatid fluid , cerebrospinal fluid(CSF) and serum of craniopharyngioma and its significance .[Methods]Turbidimetry immu‐noassay and double‐antibody sandwich ELISA were used to measure the levels of hs‐CRP in hydatid fluid ,CSF and serum of 22 patients with ameloblast craniopharyngioma and 6 patients with squamous papillary cranio‐pharyngioma ,respectively .The results were analyzed by statistical method .[Results]The levels of hs‐CRP in hydatid fluid ,CSF and serum of ameloblast craniopharyngioma were (42 .81 ± 8 .96) × 105 pg/mL ,(0 .35 ± 0 .06)× 105 pg/mL and (17 .23 ± 5 .45)× 105 pg/mL respectively ,and those in squamous papillary craniophar‐yngioma were (34 .25 ± 9 .88)× 105 pg/mL ,(0 .34 ± 0 .06)× 105 pg/mL and (16 .07 ± 9 .47)× 105 pg/mL re‐spectively .The levels of hs‐CRP in hydatid fluid of craniopharyngioma were significantly higher than those in CSF and serum( P <0 .01) .There was no significant difference in hs‐CRP between two pathological types of craniopharyngioma( P >0 .05) .[Conclusion] The significantly higher level of hs‐CRP in hydatid fluid of cra‐niopharyngioma than that in cerebrospinal fluid and serum suggests that stimulation by inflammation sub‐stances in hydatid fluid may be related to the tumor tissue inflammation .There is no significant difference in hs‐CRP level of hydatid fluid among different pathological types of craniopharyngioma .It indicates that the in‐flammatory severity in tumor hydatid fluid can not explain the diversity of craniopharyngioma tissue inflamma‐tion with different pathological types .
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2015, Vol. 32 
