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| Effects of Subglottic Secretion Drainage on the Morbidity of Ventilator-associated Pneumonia in Mechanically Ventilated Patients |
| WA NG Yu%LIU Wei |
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Abstract [Objective]To assess the effects of subglottic secretion drainage on the morbidity of ventilator‐associated pneumonia (VAP) in mechanically ventilated patients .[Methods]A total of 84 patients undergoing mechanical ventilation in Emergency Intensive Care Unit (EICU ) were randomly divided into two groups of subglottic secretion drainage (SSD ,n =41) and routine care (non‐SSD ,n=41) .Bacterial culture of samples from oropharynx ,subglottic secretions and lower respiratory tract were obtained periodically .The bacterial a‐mount of subglottic secretion ,ventilation duration ,hospitalization time and count of VAP were recorded .Eti‐ologic diagnosis of VAP was based on the quantitative bacterial culture of secretions obtained by protected specimen brush (PSB) .[Results]Group SSD had a lower rate of early‐onset VAP ,fewer ventilated days ,less hospitalization time and lower mortality rate than those of non‐SDD group ( P <0 .05) .The bacterial amount of subglottic secretion was lower in SDD group than that in non‐SDD group ( P<0 .05) .And the pathogenetic organisms were similar in subglottic secretion and lower respiratory tract .[Conclusion] The presence of sub‐glottic secretion may be an origin of pathogenetic organisms of VAP .SDD may reduce the incidence of VAP and fatality rate ,delay the onset of VAP and shorten mechanical ventilation time .And SSD is a simple and ef‐fective method of preventing VAP .
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. [J]. JOURNAL OF CLINICAL RESEARCH, 2014, 31(11): 2283-2283. |
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2015, Vol. 32 
