Abstract Objective] To understand the resistance of clinical isolates obtained from Changsha maternal and child health hospital in 2013 to commonly used antimicrobial agents .[Methods]Kirby‐Bauer(K‐B) method was used for anti‐bacterial drug susceptibility test of 1882 stains of bacteria isolated from our hospital in 2013 .According to 2013 national committee for clinical and laboratory standards institute(CLSI) ,the results were analyzed .[Results] A total of 1882 pathogenic strains were clinically isolated and included 557 Gram‐positive bacteria(29 .60% ) ,803 Gram‐negative bacteria (42 .67% ) and 522 fungi(27 .73% ) .Among Gram‐positive bacteria ,the detection rate of methicillin resistant staphylo‐coccus aureus(MASA) was 32 .94% ,and vancomycin and linezolid‐resistant staphylococcus aureus were not found ,and the sensitivity of staphylococcus epidermidis to oxacillin was high(90 .32% ) ,and the Enterococcus faecalis was sensitive to ampicillin and the resistant rate was 6 .25% ,and the sensitivity of Streptococcus agalactiae to ampicillin was 100% .A‐mong Gram‐negative bacteria ,Escherichia coli and Klebsiella pneumonia producing the extended spectrum beta‐lactamases (ESBLs) were not found ,and the sensitivity of Moraxelle catarrhalis to Ampicillin and Sulbactam was 100% ,and the re‐sistance rate of Haemophilus influenzae to Ampicillin and Sulbactam was 8 .51% .[Conclusion] Regular surveillance of bacterial drug resistance is helpful to understand the transition of bacterial drug resistance and can provide a theoretical ba‐sis for rational administration .
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