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Abstract Objective] To understand clinical characteristics and T lymphocyte subsets of severe adenovirus(ADV) pneumonia in children .[Methods]Clinical characteristics and immune‐related indicators of 101 pediatric patients with se‐vere ADV pneumonia and 122 pediatric patients with non‐severe ADV pneumonia from Jan .2013 to Dec .2013 were ana‐lyzed retrospectively .[Results] Among pediatric patients with severe ADV pneumonia ,male patients were more than fe‐male patients .Severe ADV pneumonia mainly occurred in winter and spring .There were significant differences in hospital day ,neutrophil ,c‐reactive protein(CRP) and procalcitonin(PCT) between severe ADV pneumonia group and non‐severe ADV pneumonia group( P<0 .05) .The constituent ratios of the decreasing of CD3 and CD4 in pediatric patients with severe ADV pneumonia were higher than those in pediatric patients with non‐severe ADV pneumonia ,and there was sig‐nificant difference( P<0 .05) .The constituent ratio of the increasing of CD8 in severe ADV pneumonia group was lower than that in non‐severe ADV pneumonia group ,and there was significant difference( P <0 .05) .[Conclusion]Pediatric patients with severe adenovirus pneumonia have strong inflammatory process ,the decreased immunologic responsiveness and immunity function disturbance .Early detection of the correlative indicators should be strengthened in clinical practice . Intervention and comprehensive treatment should be given to control the development of the disease .
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2014, Vol. 31 
