|
Abstract Objective] To explore the relationship between early‐onset (< 34 weeks of gestation) pre‐eclampsia and pregnancy outcome in order to identify the associated factors of early‐onset preeclampsia .[Methods]Clinical data of 25360 pregnant and lying‐in women who were enrolled in the study of gynecological and obstetrical department in our hospital from Jan .2008 to Jan .2013 were analyzed retrospectively .The cor‐related factors of early‐onset preeclampsia were analyzed .The influence on pregnancy outcome was analyzed .[Results] There were 96 pregnant women with early‐onset preeclampsia(0 .37% ) .Among them ,12 women delivered after 34 weeks of gestation .The maternal age(≥35 years old ,P=0 .006 ,95% CI ,1 .309~5 .135) , primiparity( P ≤0 .001 ,95% CI ,2 .525~5 .052) ,diabetes mellitus( P ≤0 .001 ,95% CI ,2 .029~8 .669) , chronic hypertension( P ≤0 .001 ,95% CI ,9 .112~37 .303) and congenital anomalies( P ≤0 .001 ,95% CI , 2 .632~11 .222) were high risk factors of early‐onset preeclampsia .The poor outcome in women with early‐onset preeclampsia was severer than that in women without early‐onset preeclampsia .The factors associated with the fatality of neonates were fetal death ,small for gestational age infant and perinatal death .[Conclu‐sion]Based on the correlated factors and possible pregnancy outcome of early‐onset preeclampsia ,the condition of pregnant and lying‐in women can be distinguished as early as possible ,and the pregnancy outcome can be prevented and intervened .
|
|
|
|
|
|
2014, Vol. 31 
