Abstract To explore the effect of early massage combined hyperbaric oxygen therapy ,hydro-therapy on recent nerve motor function of severe neonatal hypoxic-ischemic encephalopathy(HIE) .[Methods]Totally 497 patients with HIE were collected .According to the treatment methods ,all patients were divided into group A ,B and C .Group A received simple early massage ,and group B received massage combined with hyperbaric oxygen therapy ,and group C received massage combined with hydrotherapy .Motor function ,nerve 20-item score criteria(NBNA) score ,body weight ,height ,daily milk intake after treatment were compared a-mong 3 groups .[Results]After treatment ,the proportion of taking grade Ⅲ action in group A was obviously lower than that in group B and group C( P <0 .05) ,but there was no significant difference between group B and group C( P>0 .05) .NBNA scores in group B and group C at 2 and 4 weeks after treatment were signifi-cantly higher than those in group A ( P <0 .05) ,but there was no significant difference in NBNA score be-tween group B and group C( P>0 .05) .The weight ,height and daily milk intake in group B and group C at 4 weeks after treatment were significantly better than group A ( P <0 .05) ,but there was no significant differ-ence between group B and group C( P>0 .05) .[Conclusion]Early massage combined with hyperbaric oxygen or hydrotherapy can promote neural motor function rehabilitation in pediatric patients with HIE and is condu-cive to neonatal growth and development .Therefore ,it is worthy of clinical promotion .
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