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Abstract To explore the efficacy of fluoxetine hydrochloride combined with Xiaoyao pill for the treatment of postpartum depression in puerperas after induction of labor in second trimester .[Methods]A total of 52 puerperas with postpartum depression after induction of labor in second trimester were randomly divided into control group and observation group with 26 cases in each group .The control group was only treated with fluoxe-tine hydrochloride ,while the observation group was treated with fluoxetine hydrochloride and Xiaoyao pill .The treatment in two groups lasted four weeks .The efficacy and adverse reaction of two treatment methods were as-sessed by Hamilton depression scale(HDMA) and adverse reaction scale(TESS) .[Results]The total effective rate of the observation group was 96 .15% ,which was higher than that(92 .31% ) of the control group( P>0 .05) ,but the full recovery rate of the observation group was significantly higher than that of the control group ( P<0 .05) . With the prolongation of treatment time ,the deducted rate of HDMA in two groups was increased gradually ( P<0 .05) .The TESS score in observation group at 1st and 2nd week after treatment was obviously less than that in control group[(6 .87 ± 2 .38 ,6 .06 ± 2 .71) vs .(9 .12 ± 3 .03 ,8 .01 ± 2 .97)]( P <0 .05) .[Conclusion] The part-ner treatment of Xiaoyao pill can increase the efficacy of fluoxetine hydrochloride for the treatment of postpartum depression and decrease the adverse reaction in a certain degree .
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2014, Vol. 31 
