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Abstract To analyze the change of serum homocysteine(Hcy) in patients with type 2 diabetic nephropathy and its significance .[Methods] Patients with type 2 diabetes mellitus in our hospital from Feb . 2012 to Dec .2013 were selected .According to urinary albumin excretion rate(UAER) determination results , all patients were divided into group A (simple diabetic group) ,group B(diabetes mellitus with early nephropa-thy) ,group C(diabetes mellitus with clinical nephropathy ) and group D(normal healthy control group) .FBG , SCr ,BUN and Hcy were measured and analyzed by statistics .[Results] Compared with control group ,Hcy levels in group A ,B and C were markedly increased ,and there was significant difference( P <0 .05) .[Con-clusion] Hyperhomocysteinaemia is an independent risk factor of type 2 diabetic nephropathy .
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2014, Vol. 31 
