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Abstract To explore the clinical efficacy of azintamide combined with gastrointestinal motili-ty drug mosapride for the treatment of bile reflux gastritis .[Methods]Totally 120 patients with bile reflux gastritis in our hospital from Dec .2011 to Dec .2013 were selected and randomly divided into control group ( n=60) treated with aluminum magnesium carbonate and mosapride and the observation group ( n=60) treated with azintamide and mosapride .Clinical efficacy was compared between two groups .[Results] After treat-ment ,the total effective rate in observation group was 86 .67% ,which was significantly higher than that in control group ,and there was significant difference between two groups ( P < 0 .05) .Compared with control group ,the symptom scores in observation group were obviously improved ,and there was significant difference between two groups( P < 0 .05) .The frequency of bile reflux and most general reflux time in observation group were obviously lower than those in control group ,and there was significant difference ( P < 0 .05) .[Conclusion] Azintamide combined with gastrointestinal motility drug mosapride can not only promote regular bile secretion ,but also increase gastrointestinal motility and food digest ability ,improve clinical uncomfortable symptoms and is helpful for the improvement of pathogenetic condition and quality of life through the synergis-tic effect .Therefore ,it is worthy of clinical application .
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2014, Vol. 31 
