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Abstract To explore the effect of one-lung ventilation (OLV ) with pressure control ventilation-volume guarantee(PCV-VG) on respiratory mechanics in elderly patients undergoing radical esophageal cancer sur-gery .[Methods] Totally 40 elderly patients(ASA Ⅰ ~ Ⅱ) undergoing radical esophageal cancer surgery were di-vided into two groups with 20 in each .All patients were given sevoflurane inhalation for maintenance anesthesia and intubated with double lumen endotracheal catheter .Two-lung volume controlled ventilation(VCV) with a tidal volume(VT) of 10ml/kg and frequency(f) of 12 breaths per minute were performed before chest opening .After chest was opened ,OLV was performed .Group A received VCV mode with a VT of 8ml/kg and f of 12 breaths per minute .Group B received PCV-VG mode with the same peak airway pressure (Ppeak) as that during two-lung VCV ,VT of 8ml/kg and f of 12 breaths per minute .The VT ,minute volume(MV) ,Ppeak ,mean airway pres-sure(Pmean) ,end-tidal pressure of carbon dioxide (PET CO2 ) and dynamic lung compliance (Cdyn) before OLA (T1 ) ,30min after OLA(T2 ) ,60min after OLA(T3 ) and 30min after two-lung ventilation(TLA) were observed . Lung effective dynamic compliance(Cdyn) was calculated .[Results]Compared with group A ,Ppeak and Pmean in group B were decreased ,but there was no significant difference in VT ,MV and PET CO2 ,and Cdyn was increased .[Conclusion] PCV-VG mode in OLA for elderly patients undergoing radical esophageal cancer surgery can decrease Ppeak ,ensure ventilatory capacity and improve Cdyn ,so it is good for lung protection in elderly patients .
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2014, Vol. 31 
