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Abstract Objective To explore the protective effect of nifedipine on brain injury in patients with cere-bral hemorrhage .[Methods] A total of 58 patients with cerebral hemorrhage were randomly divided into rou-tine treatment group and nifedipine treatment group .Clinical neurologic impairment score ,Barthel index (BI) score ,hematoma volume and edema area volume of patients before and after treatment were observed .[Re-sults] Total effective rate of nifedipine group was 75% ,which was markedly higher than that of routine treat-ment group(60% ) .Compared with routine treatment group ,the decline value of clinical neurological impair-ment score and BI score were elevated and the dependency level of daily living activity was markedly reduced in nifedipine group after treatment .Hematoma volume in two groups after treatment was obviously decreased , but there was no significant difference in the decline value of hematoma volume between two groups after treat-ment .Edema area of two groups after treatment was also decreased ,but the decline value of edema area vol-ume in nifedipine group was obviously elevated .[Conclusion] Nifedipine can obviously alleviate brain edema , protect nerve cells ,decrease neurologic impairment level and improve quality of life of patients with cerebral hemorrhage .
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2014, Vol. 31 
