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Abstract Objective To explore the correlation between subclinical hypothyroidism and chronic complications of type 2 di-abetes mellitus(T2DM ) .[Methods] Totally T2DM patients with subclinical hypothyroidism (hypothyroidism group) were cho-sen .Other 50 T2DM patients without subclinical hypothyroidism (control group) were chosen randomly .Biochemical indexes and complications were compared between two groups .[Results] Age ,sex ratio ,duration of diabetes mellitus and the inci-dence of coronary heart disease in hypothyroidism group were obviously higher than those in control group .The levels of total cholesterol(TC) ,triglyeride(TG) ,low density lipoprotein cholesterol(LDL-C) 24h-urinary albumin excretion rate(UAER) , high sensitive C-reactive protein(hs-CRP) ,thyroid stimulating hormone(TSH) ,thyroid peroxidase antibody(TPO-Ab) and thyroglobulin antibody(TG-Ab) in hypothyroidism group were obviously higher than those in control group ,but ankle/brachial index(ABI) and the ratio of E peak(cardiac rapid filling period) to A peak(cardiac slow filling period) in hypothyroidism group were lower than those in control group( P<0 .05) .There was no significant difference in the incidence of diabetic retinopathy (DR) between two group .The incidence rates of diabetic nephropathy (DN) ,diabetic polyneuropathy(DPN) and diabetic pe-riphery artery disease(PAD) in hypothyroidism group were significantly higher than those in control group [Conclusion] Pa-tients with T2Dm is easy to have subclinical hypothyroidism .Subclinical hypothyroidism may affect the occurrence of chronic complications of diabetes mellitus .
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2014, Vol. 31 
