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Abstract [Objective]To explore the influence of physiological pacing(DDD)and non-physiological pa-cing(VVI)on cardiac structure and N-terminal pro-brain nitric peptide(NT-proBNP)in order to accumulate the experience for the coping strategies after cardiac pacemaker implantation.[Methods]A total of 6 5 patients treated with pacemaker in cardiology department of our hospital from Jan.2012 to Dec.2012 were chosen. According to different pacing mode,all patients were divided into two groups.The control group was treated with VVI,while the study group was treated with DDD.Left ventricular structure and NT-proBNP in two groups before and after pacemaker implantation were recorded and compared.[Results]There was no signifi-cant difference in LAD,LVD,IVST,PWT and EF before pacemaker implantation between two groups(P>0.05).After pacemaker implantation,LAD in the study group was lower than that in the control group(P<0.05),while EF in the study group was higher than that in the control group(P<0.05).There was no sig-nificant difference in NT-proBNP before pacemaker implantation between two groups(P>0.05).After pace-maker implantation,NT-proBNP in the study group was lower than that in the control group (P <0.05).[Conclusion]Patients with the indications of pacemaker should be treated with atrial-ventricular sequential pa-cing in order to reduce the effect of pacing on cardiac structure and function.
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2014, Vol. 31 
