Abstract [Objective]To explore the efficacy ,safety ,complication and prognosis of surgical treatment of hepatocellular carcinoma(HCC) with liver cirrhosis .[Methods] Totally 57 HCC patients with liver cirrhosis undergoing surgical treatment in our hospital from Jan .2001 to Aug .2008 were enrolled in the study .A ret-rospective analysis method was used to analyze all data of patients before and after surgery .The year survival rate was calculated .Univariate and multivariate regression method was used to analyze the influencing factors of year survival rate of patients .[Results] The 1-year ,2-year ,3-year and 5-year survival rate of patients after surgery was 63 .6% ,52 .1% ,34 .7% and 19 .3% ,respectively .Preoperative child grading ,preoperative platelet count ,preoperative alpha-fetoprotein(AFP) measurement ,tumor size and whether radical resection or not were all correlated with the prognosis ( P<0 .05) .Preoperative child grading and whether radical surgery or not was an independent risk factor ( P <0 .05) .[Conclusion]Surgery is the ideal method of radical treat-ment of HCC with liver cirrhosis ,but accurate preoperative assessment of patients'liver functional reserve and postoperative active adjuvant therapy is the key to improve survival rate and quality life of the patients .
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