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Abstract [Objective] To explore clinical efficacy of stomach tube injection of pralidoxime iodide and mannitol applied in patients with organophosphorus pesticide poisoning .[Methods]Totally 60 patients with organophosphorus pesticide poisoning were randomly divided into observation group ( n=32) and control group( n =28) .The control group was given routine gastric lavage ,atropine ,pralidoxime iodide injection ,fluid infusion and symptomatic treat-ment .The observation group was given gastric lavage tube injection of pralidoxime iodide (or chlorophos) and manni-tol based on the above treatment .Clinical efficacy was compared between two groups .[Results] Atropine dosage and the frequency of bounce in observation group were obviously less than those in control group ( P<0 .01) ,while atro-pinization time ,hospitalization time ,curative rate and mortality in observation group were better than those in control group( P<0 .05) .[Conclusion]Early gastric lavage tube injection of pralidoxime iodide (or chlorophos ) and mannitol can obviously improve the rescue successful rate of organophosphorus pesticide poisoning .
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2014, Vol. 31 
