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Evaluation of the Efficacy of Bifid Triple Viable Capsule Combined with Mesalazine in the Treat-ment of Ulcerative Colitis |
ZHANG Chen%ZOU Yi-you |
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Abstract [Objective] To evaluate the efficacy of bifid triple viable capsule combined with mesalazine in the treatment of ulcerative colitis in many aspects of clinical manifestation ,colonoscopy and the changes of intestinal flora .[Methods]Totally 92 patients with ulcerative colitis patients in our hospital were divided into two groups by random digital table classification .The control group was given mesalazine only ,while the observation group was given mesalazine combined with bifid triple viable capsule .Clinical symptom scores ,intestinal flora and colonosco-py scores before and after the treatment were compared between two groups .[Results]The total effective rate of the observation group and control group was 89 .13% and 58 .7% ,respectively .The efficacy of observation group was obviously better than the control group ( P <0 .05) .After the treatment ,the decreasing degree of symptom scores and colonoscopy scores in observation group was larger than that in control group ( P<0 .05) .The number of lactobacillus and bifid bacterium in observation group after treatment were increased obviously ,but the number of Escherichia coli and Enterococcus were decreased obviously ( P<0 .05) .[Conclusion]Bifid triple viable capsule combined with mesalazine is benefit for the balance of intestinal flora ,and thus can inhibit the inflammation and significantly improve the curative effect .
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. [J]. Journal of Clinical Research, 2013, 30(7): 1454-1455. |
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