Abstract [Objective] To explore the correlation between metabolically healthy obese(MHO) and nonal-coholic fatty liver disease(NAFLD) .[Methods] The data of physical examination subjects in our hospital from April 2006 to Jan .2010 were collected .All clinical indicators ,biochemical indexes and abdominal B-ultrasound results of subjects were recorded .There were 2830 cases excluding those with the missing data .According to the diagnostic criteria of obesity ,613 subjects including 261 cases of M HO and 352 cases of MS were enrolled in the study .General data such as blood pressure ,blood sugar ,lipids ,uric acid and white blood cell count (WBCC) in peripheral blood of 134 cases of M HO with NAFLD ,127 cases of M HO without NAFLD and 352 cases of MS were analyzed .Among them ,109 cases of MHO(including 62 cases of MHO with NAFLD) were followed up for 1~3 years .The incidence of MS in M HD with NAFLD was observed .[Results]Body mass in-dex(BMI),ageandsystolicbloodpressure(SBP)inthegroupofMHOwithoutNAFLDwerelowerthanthose in the group of M HO with NAFLD ,and there was significant difference( P<0 .05) .There was no significant difference in BMI and age between the group of MHO with NAFLD and the group of obesity with MS .SBP in the group of M HO with NAFLD was lower than that in the group of obesity with MS ,but higher than that in the group of MHO without NAFLD ,and there was significant difference ( P<0 .05) .The incidence of abnor-mal metabolic diseases in the group of M HO with NAFLD was higher than that in the group of M HO without NAFLD(59 .68% vs .29 .79% ,OR=3 .489 ,95% CI:1 .559~7 .804 ,P <0 .05) .[Conclusion] Clinical and biochemical features of the subjects with M HO and NAFLD is closer to those of the subjects with obesity and MS .NAFLD may be a risk factor of M HO developing to abnormal metabolic diseases .
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