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Abstract [Objective] To explore the relationship of carotid intima-media thickness(IMT) with serum inter-leukin-6(IL-6) in patients with impaired glucose tolerance(IGT) .[Methods] According to carotid IMT ,297 IGT patients were divided into normal IMT group(n=103 ,IMT<1 .0mm) ,IMT thickening group( n=99 ,1 .0mm 1 .3mm) .Other 100 healthy subjects were chosen as control group .Serum IL-6 was determined .[Results] Serum IL-6 in IGT group was higher than that in control group(p<0 .01) ,but there was no significant difference in IL-6 between normal IMT group and control group( P>0 .05) .In IGT group ,serum IL-6 in IM T thickening patients was markedly higher than that in normal IMT group( P <0 .01) .The positive correlation between IL-6 and IMT was shown in both IMT thickening group and atherosclerotic plaque group(r was 0 .567 and 0 .682 respectively ,P<0 .01) .[Conclusion] Serum IL-6 in IGT patients may have some correlation with early atherosclerosis .
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2014, Vol. 31 
