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Abstract [Objective] To observe the efficacy of patient-controlled intravenous analgesia (PCA ) ,succinic acid solifenacin tablet and tolterodine tartrate sustained release tablet combined with PCA for the treatment of cystospasm after transurethral prostatic resection(TURP) .[Methods] Totally 80 patients after TURP in our hospital were ran-domly divided into 4 groups .The control group was given pethidine 50mg and anisodamine 10mg by muscle injection . PCA group was given continuous venous injection with sufentanil 100μg and granisetron 6mg by vein analgesia pump , which were diluted to 100mL with normal saline ,and the dosage was adjusted into 2mL by constant speed for 72h . Solifenacin group was given oral succinic acid solifenacin tablet 5mg for once a day .The combination group was given oral tolterodine tartrate sustained release tablet 2mg for once a day and PCA therapy .Clinical efficacy was compared among groups .[Results]The frequency and mean duration of cystospasm and bladder washout times in 3 experimental groups d1 ,d2 and d3 after operation were shorter than those in control group .The frequency and mean duration of cystospasm in combination group were shorter than those in PCA group and solifenacin group ,and there was signifi-cant difference among groups (all P<0 .05) .There was no significant difference in all indicators between PCA group and solifenacin group( P>0 .05) .[Conclusion]PCA ,succinic acid solifenacin tablet and tolterodine tartrate sustained release tablet combined with PCA for the prevention and treatment of early cystospasm after TURP have good effica-cy .The combination group has more significant efficacy and should be promoted in clinical practice .
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2014, Vol. 31 
