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Abstract [Objective] To explore the detection rate and drug resistance of Escherichia coli in urinary tract infection of our region in order to provide the evidence for clinical rational administration .[Methods]The drug susceptibility results of 208 strains of Escherichia coli and extended-spectrum beta-lactamases(ESBLs) isolated from medistream urine of inpatients with urinary tract infection in our hospital between Jan .2010 and Dec . 2011 were analyzed .[Results] The 208 strains of Escherichia coli were isolated and identified .Among them , 109 strains were producing-ESBLs(52 .4% ) .The sensitivity of producing-ESBLs from Escherichia coli to Mer-openem ,imipenem ,Cefoperazone/sulbactam ,Amikacin ,piperacillin/tazobactam and cefoxitin were higher , and the drug resistance rate of producing-ESBLs strains from Escherichia coli was obviously higher than that of non-ESBLs strains .[Conclusion] The drug resistance of Escherichia coli in urinary tract infection is high ,es-pecially for producing ESBLs strains .Strengthening the monitoring of producing ESBLs strains is of important significance for clinical medication and the controlling of the spread of resistant strains .
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2014, Vol. 31 
