摘要【目的】探讨肿瘤神经侵犯(PNI)与食管癌患者预后的相关性。【方法】回顾性分析本院收治的162例食管鳞癌患者的临床病理资料,采用Cox多因素回归模型分析食管鳞癌预后的相关因素。应用Kaplan Meier法比较PNI食管鳞癌患者生存的差异。【结果】PNI食管癌患者5年无病生存率显著低于无PNI者(22.7% vs 40.7%, P<0.01),5年总生存率显著低于无PNI者(22.5% vs 44.9%, P<0.01)。Cox多因素回归分析显示PNI是食管癌患者无病生存及总生存的独立影响因素(HR=1.449、1.735,均P<0.05)。有PNI的Ⅱ期食管鳞癌患者和Ⅲ期无PNI患者的无病生存率和总生存率相比较差异均无显著性(P> 0.05)。【结论】PNI是食管癌患者预后的独立影响因素。
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2020, Vol. 37 
