Clinical Efficacy of Escitalopram Combined with Electrical Stimulation Aversion Therapy on Refractory Obsessive-compulsive Disorder:31 Cases of Clinical Report
ZHENGLin, TIANYue, CHENGAO-bo, et al
Kailuan Mental Health Center Affiliated to North China University of Science and Technology,Tangshan 063000
Abstract：【Objective】 To investigate the effect of escitalopram combined with electrical stimulation aversion therapy on refractory obsessive-compulsive disorder. 【Methods】 From January 2017 to January 2018, 62 cases of patients with refractory obsessive-compulsive disorder were studied in our hospital. According to the simple random method, they were divided into two groups, 31 cases in each group; the control group was treated with escitalopram, and the observation group was treated with escitalopram combined with electric stimulation aversion therapy. The therapeutic effects, the Yale-Brown compulsion scale, HAMA scale score, and the incidence of adverse reactions during treatment were compared between the two groups. 【Results】 The effective rate of the control group was 74.29%, the effective rate of the observation group was 93.55%, and the effective rate of the observation group was higher than that of the control group (P<0.05). The scores of the Yale-Brown and HAMA scales in the two groups were lower than those before the treatment (P<0.05), and the score of the Yale-Brown compulsion scale in the observation group was lower than that of the control group (P<0.05), and there was no statistical difference between the two groups after the treatment (P>0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). 【Conclusion】 Escitalopram combined with electrical aversion therapy is effective in treating obsessive-compulsive disorder. It can effectively improve the clinical symptoms of patients with high safety.
2018, Vol. 35 
