摘要【目的】探讨腹腔镜直肠癌前切除术中低位结扎肠系膜下动脉(IMA)时保留左结肠动脉(LCA)的临床疗效。【方法】回顾性分析2014年6月至2017年12月本院收治的122例行腹腔镜直肠癌前切除术患者的病例资料,其中保留左结肠动脉56例(低位结扎组),不保留左结肠动脉66例(高位结扎组)。观察记录两组手术时间、术中出血量、肠系膜血管根部淋巴结清扫数、淋巴结阳性率、术后恢复排气时间、住院天数、吻合口瘘发生情况。【结果】两组患者均顺利完成腹腔镜手术,无中转开腹,术中术后无死亡病例,并未出现严重并发症。低位结扎组与高位结扎组手术时间[(117.6±16.5)min vs(95.2.6±18.4)min]、术后吻合口瘘发生率(0 vs 6.1%)比较,差异有统计学意义(均P<0.05)。两组术中出血量、清扫肠系膜下血管根部淋巴结数量、淋巴结阳性率、术后恢复排气时间及住院天数方面比较,差异无统计学意义(均P>0.05)。【结论】保留左结肠动脉在腹腔镜直肠癌前切除术中能为结肠吻合口血运提供更好的保障,并可以完成同样彻底的淋巴结清扫,其有临床推广价值。
[1] Lowry AC, Simmang CL, Boulos P, et al. Consensus statement of definitions for anorectal physiology and rectal cancer[J].ANZ J Surg,2001,71(10):603-605. [2] 臧潞,马君俊,郑民华.直肠癌根治术中保留左结肠动脉对吻合口瘘及手术时间的影响[J].中华胃肠外科杂志,2016,19(4):386-387. [3] Sekimoto M, Takemasa I, Mizushima T, ,et al. Laparoscopic lymph node dissection around the inferior mesenteric artery with preservation of the left colic artery [J].Surg Endosc. Laparoscopic lymph node dissection around the inferior mesenteric artery with preservation of the left colic artery [J].Surg Endosc,2011,25(3)861-866. [4] Hinoi T, Okajima M, Shimomura M, et al. Effect of left colic artery preservation on anastomotic leakage in laparoscopic anterior resection for middle and lou rectal cancer[J]. World J Surg,2013,37(12):2935-2943. [5] Titu LV, Tweedle E, Rooney PS.High tie of the inferior mesenteric artery in curative surgery for left colonic and rectal cancers: a systematic review[J].Dig Srug ,2008,25(2);148-157. [6] Lange MM, Buunen M, van de Velde CJ, et al. Level of arterial ligation in rectal cancer surgery: low tie preferred over high tie. A review[J]. Dis Colon Rectum,2008,51(7):1139-1145. [7] 邵春法,谢健进,徐美东,等. 直肠癌前切除术后吻合口漏原因的多因素分析[J]. 中华微创外科杂志,2011,11(5):400-402. [8] Mari G, Maggioni D, Costanzi A, et al. “High or low inferior Mesenteric Artery ligation in Laparoscopic low Anterior Resection:study protocol for a randomized controlled trial” (HIGHLOW trial)[J] .Trials, 2015,16:21. [9] Seike K, Koda K, Saito N, et al. Laser Dopple assessment of the influence of division at the root of the inferior mesenteric artery on anastomotic blood flow in rectosigmoid cancer surgery[J]. Int J Colorectal Dis ,2007,22(6);689-697. [10] Lange JF, Komen N, Akkerman G, et al. Riolan,s arch: confusing, misnomer, and pbsolete. A literature survey of the connection (s) between the superior and inferior mesenteric arteries[J]. Am J Surg, 2007,193(6):742-748. [11] Buunen M, Lange MM, Ditzel M,et al, Level of arterial ligation in total mesoretal excision(TME): an anatomical study[J]. Int J Coloretal Dis, 2009,24(11);1317-1320. [12] Chin CC, Yeh CY, Tang R, et al. The oncologic benefit of high ligation of the inferior mesenreric artery in the surgical treatment of rectal or sigmoid colon cancer[J].Int J Colirectal Dis, 2008,23(8):783-788.