Abstract：【Objective】To investigate the incidence of leukopenia in DCD (organ donation after cardiac death) recipients after renal transplantation. 【Methods】We retrospectively analyzed the clinical data of 83 DCD recipients from January 2012 to January 2017 who underwent renal transplantation in our hospital. According to whether or not ganciclovir was administered, patients were divided into the observation group (immunosuppressive agents + ganciclovir,n=62) and the control group (immunosuppressive group only,n=21). The occurrences of leukopenia in both groups were statistically analyzed. 【Results】In the observation group, leukopenia occurred in 22 cases (35.48%), including a mild 10 cases (16.13%), a moderate 6 cases (9.68%), a severe 4 cases (6.45%), and a critical 2 cases (3.23%). In the control group, neutropenia occurred in 3 patients (14.29%), including 1 mild case (4.76%), 1 moderate case (4.76%), 1 severe case (4.76%), and 0 critical cases. The incidence of leukopenia in the control group was significantly lower than that in the observation group (χ2=5.152,P=0.015<0.05). Except for one case of critical leukopenia with death, the white blood cells in all other cases returned to normal after treatment. 【Conclusion】The reduction of leukopenia after renal transplantation in DCD recipients is common, and the combined use of immunosuppressants with antiviral drugs is one of the common causes. Most patients can recover to normal levels after symptomatic treatment.
2018, Vol. 35 
