Abstract：【Objective】To compare the effects of intracoronary injection of adrenalin or verapamil on slow blood flow during percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (AMI).【Methods】The clinical data of 98 AMI patients treated with PCI from June 2016 to June 2017 were analyzed retrospectively. All patients were treated with PCI. The patients were divided into two groups: group A (intracoronary injection of epinephrine) and group B (intracoronary injection of verapamil). The coronary blood flow, serum inflammatory factor level and cardiovascular adverse events were compared between the two groups.【Results】There was no significant difference in the number of vessel branches between the two groups (P>0.05). The recovery rate of grade Ⅲ TIMI in the group A was significantly higher than that in the group B, and the blood flow time to grade Ⅲ TIMI was lower in the group A than in the group B. The difference was statistically significant (P<0.05). The levels of serum hypersensitive C-reactive protein (hs-CRP) and creatine kinase isoenzyme (CK-MB) were significantly lower in the group A than the in the group B after PCI. There was no significant difference in the levels of NT-proBNP and cTnT between the two groups(P＞0.05). The incidence of cardiovascular adverse events in the group A 6.12％(3/49) was significantly lower than that the in the group B 12.24%(6/49), and the difference was statistically significant (χ2=7.354,P=0.017＜0.05).【Conclusion】Both adrenalin and verapamil can improve the slow blood flow in patients with myocardial infarction (PCI), while adrenalin injection has better effect and safety.
张喆, 何建新, 邱健. 冠脉内注射肾上腺素和维拉帕米对心肌梗死患者PCI术中慢血流的影响[J]. 医学临床研究, 2018, 35(5): 842-844.
ZHANG Zhe, HE Jian-xin, QIU Jian. Comparison of Intra-coronary Injection of Different Drugs on Slow Blood Flow in Patients with Myocardial Infarction. JOURNAL OF CLINICAL RESEARCH, 2018, 35(5): 842-844.
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2018, Vol. 35 
