Abstract：【Objective】To investigate the correlation between the basic amount of initial intensive insulin pump therapy and body mass index (BMI), glycosylated hemoglobin (HbA1c) in patients with newly diagnosed type 2 diabetes mellitus (T2DM).【Methods】From January 2015 to June 2017, 93 newly diagnosed T2DM patients in Department of Endocrinology, Guangdong Provincial Hospital of traditional Chinese Medicine, receiving intensive insulin pump therapy, were selected, and the general data of the patients were collected. BMI and WHR were calculated. Serum biochemical indexes were detected by automatic biochemical analyzer, whole blood HbA1c was measured by HPLC, fasting blood glucose (FBG) and 2 h postprandial blood glucose (2hPGG) were monitored during treatment. The correlation between the basic quantity of insulin pump and clinical index was analyzed.【Results】After intensive treatment with insulin pump, 72 patients reached the standard of blood glucose and 21 patients failed to reach the standard. The BMIs, the total amount of insulin pump and the basic quantity of insulin pump were significantly lower than those in the substandard group (P<0.05). There was a positive correlation between the basal insulin pump level and the course of BMI, FPG, 2hPG and HDL-C (mean P<0.05), and a negative correlation with low density lipoprotein cholesterol (LDL-C) (P<0.05), and no correlation with age, WHR, HbA1c, TC, TGs (mean P>0.05).【Conclusion】For patients newly diagnosed with type 2 diabetes, BMI is associated with the basal volume of initial insulin pump therapy and can be used as a reference indicator of basal insulin pump volume.
黄国圣,张锦明,赵玲,宋薇. 新诊断2型糖尿病患者胰岛素泵基础量与BMI、HbA1c的相关性分析[J]. 医学临床研究, 2018, 35(3): 498-500.
HUANG Guo-sheng, ZHANG Jin-ming, ZHAO Lin, et al. Correlation Analysis of Insulin Pump Base Amount and BMI,HbA1c in Patients with Newly Diagnosed Type 2 Diabetes. JOURNAL OF CLINICAL RESEARCH, 2018, 35(3): 498-500.
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2018, Vol. 35 
