Abstract：【Objective】To investigate the diagnostic value of magnetic resonance diffusion imaging (MR-DWI) combined with intestinal ultrasonography (TRUS) in prostate cancer and its application in Gleason classification.【Methods】From June 2015 to July 2017, 98 patients with benign and malignant prostatic diseases were studied. MR-DWI and TRUS were performed before operation. The apparent diffusion coefficient was recorded and compared with pathological diagnosis. The sensitivity, specificity and accuracy of different detection methods were compared, and the correlation between ADC and Gleason score was analyzed.【Results】Among 98 cases, 43 cases were prostate cancer, 40 cases were benign prostatic hyperplasia, 15 cases were prostatitis. The ADC value of prostate cancer patients was significantly lower than that of prostatic hyperplasia patients and prostatitis patients. The difference was statistically significant (P<0.05). The order of ADC in different TNM stages of prostate cancer patients was Ⅰ>Ⅱ>Ⅲ>Ⅳ, but there was no significant difference between the two groups (P>0.05). The sensitivity of MR-DWI, TURS and MR-DWI+TRUS to diagnose prostate cancer were 86.0.4%, 74.48%, 95.34%, specificity 83.63%, 78.18%, 89.09%, respectively, and the accuracy rates were 84.69%, 74.49%, 91.83%, respectively. The accuracy of MR-DWI TRUS in the diagnosis of prostate cancer was the highest, which was significantly higher than that of the other two methods. The correlation analysis showed that the ADC value of prostate cancer patients was negatively correlated with Gleason score.【Conclusion】MR-DWI combined with TRUS has high accuracy in diagnosis and prognosis of prostate cancer.
吴娜娜,苟杰,胡炜,李昌林. MR-DWI联合TRUS在前列腺癌诊断及Gleason分级中的应用[J]. 医学临床研究, 2018, 35(3): 456-458,463.
WU Na-na, GOU Jie, HU Wei, et al. Application of MR-DWI Combined with TRUS in the Diagnosis and Gleason Classification of Prostate Cancer. JOURNAL OF CLINICAL RESEARCH, 2018, 35(3): 456-458,463.
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2018, Vol. 35 
