Abstract：【Objective】To explore the relationship between Gensini score and major adverse cardiac events (MACE) in patients with coronary artery disease (ACS).【Methods】A total of 78 patients with coronary artery disease (ACS) from December 2015 to July 2016 were collected for the study. Based on the incidence of MACE during the follow-up period, patients were divided into the MACE group and No-MACE group. The differences of Homocysteine (Hcy), Myeloperoxidase ( MPO) and Gensini scores between the two groups were recorded and analyzed.【Results】The MACE group had a Gensini score of (65.77±4.03), which was higher than that of non-MACE group (46.16±5.02); the difference was statistically significant (P＜0.01). Levels of Hcy and MPO in the MACE group were (18.63±4.37)μmol/L, (4149.52±955.41)pmol/L, respectively, which were higher than those in No-MACE group (15.21±2.70)μmol/L and (2302.74±1107.83)pmol/L, respectively. The differences were statistically significant (P＜0.05). Multivariate Logistic regression analysis was used to analyze the factors influencing the MACE prognosis of patients with ACS and the Hcy, MPO and Gensini scores during follow-up. The results showed that the Gensini score could be used as an independent predictor of MACE risk in ACS patients from 1 to 6 months of ACS.【Conclusion】The Gensini score has certain advantage in predicting the risk of MACE with high accuracy. It has positive correlation between the occurrence of MACE risk and Gensini score.
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2018, Vol. 35 
