[1] Liang CC,Lin PC,Lee MY,et al.Association of serum uric acid concentration with diabetic retinopathy and albuminuria in taiwanese patients with type 2 diabetes mellitus[J].Int J Mol Sci,2016,17(8):1248-1262. [2] 王镁,于世家,刘庆阳,等.大黄酸对肥胖糖尿病大鼠肾组织氧化应激的影响[J].中华中医药学刊,2011,29(7):1559-1560. [3] Kodama S,Saito K,Yachi Y,et al.Association between serum uric acid and development of type 2 diabetes[J].Diabetes Care,2009.32(9): 1737-1742. [4] Richard J Johnson,Santos E Perez-Pozo,Yuri Y Sautin,et al.Hypothesis: could excessive fructose intake and uric acid cause type 2 diabetes[J]? Endocr Rev,2009.30(1): 96-116. [5] Jayashankar CA,Andrews HP,Vijayasarathi,et al.Serum uric acid and low-density lipoprotein cholesterol levels are independent predictors of coronary artery disease in Asian Indian patients with type 2 diabetes mellitus low-density lipoprotein[J].J Nat Sci Biol Med,2016,7(2): 161-165. [6] 韩晓芳,张新秀,刘克梅,等.2型糖尿病患者血尿酸与糖尿病肾病的相关性[J].安徽医药,2016,37(7):865-866. [7] Pingmuangkaew P.Association of elevated serum uric acid with the components of metabolic syndrome and oxidative stress in abdominal obesity subjects[J].Indian J Clin Biochem,2015,30(3): 286-292. [8] Zharikov S,Krotova K,Hu H,et al.Uric acid decreases NO production and increases arginase activity in cultured pulmonary artery endothelial cells[J].Am J Physiol Cell Physiol,2008.295(5): C1183-C1190. [9] Sanchez-Lozada LG ,Lanaspa MA,Crisobal-Garcfa M,et al.Uric acid-induced endothelial dysfunction is associated with mitochondrial alterations and decreased intracellular atp concentrations[J].Nephron Exp Nephrol,2012,121(3-4):71-78. [10] Green DY,Kroemer G.The pathophysiology of mitochondrial cell death[J].Science,2004,305(5684):626-629. [11] Verzola D,Ratto E,Vollaggio B,et al.Uric acid promotes apoptosis in human proximal tubule cells by oxidative stress and the activation of NADPH oxidase NOX 4[J].PLoS One,2014,9(12): 115210-115238. [12] Cristobal-Garcia M,Garcia Arroyo FE,Tapia E,et al.Renal oxidative stress induced by long-term hyperuricemia alters mitochondrial function and maintains systemic hypertension[J].Oxid Med Cell Longev,2015,535686-535699. [13] 张涛,牛洪林,康英丽,等.高浓度尿酸对人近端肾小管上皮细胞氧化应激的影响[J].山东医药,2014,54(24): 13-15. [14] Rhyu DY,Yang Y,Ha H,et al.Role of reactive oxygen species in TGF-beta-induced mitogen-activated protein kinase activation and epithelial-mesenchymal transition in renal tubular epithelial cells[J].Am J Physiol Renal Physiol,2005,16(3):667-675. [15] Kim SM,Choi YW,Seok HY,et al.Reducing serum uric acid attenuates TGF-β1-induced profibrogenic progression in 2 diabetic nephropathy [J].Nephron Exp Nephrol,2012,121(3-4):109-121.
2018, Vol. 35 
