Abstract：【Objective】To compare acesodyne and hemostatic effects of three filling materials after function endoscopic sinus surgery in patients with chronic rhinosinusitis (CRS).【Methods】A total of 93 patients with chronic rhinosinusitis treated in our hospital from July 2013 to December 2015 were selected as the research objects. They were divided by random number table into group A, B and C (with 31 cases in each group). Function endoscopic sinus surgery was performed in all patients, vaseline gauze was used as filling materials to stop bleeding after the operation in group A, AVF expansion hemostatic sponges were used in group B, and self-made flixonase collagen sponges were used in group C. Pain VAS score, postoperative bleeding rate, epithelial process and adverse reaction rate at postoperative 4h, 12h, 24h, 48h in the three groups were compared.【Results】Group C was the lower than both groups A and B in VAS pain scores at postoperative 4h, 12h, 48h among the three groups, and the differences were statistically significant (P<0.05). The scores of groups A, B and C were (5.4±0.7)score, (4.7±0.5)score, (3.3±0.4)score respectively. The score in group B was higher than group A (P<0.05). Postoperative bleeding rates of group A, B and C were 71.0%, 64.5%, 54.8% respectively; there were no significant differences (P>0.05). Among the three groups, group C was the highest in mucous epithelization of operative cavity rate 3 months and 6 months after the operation; they were 71.0%, 96.8% respectively, which were higher than group A and B (all P<0.05), while there was no significant difference in group A and B (P>0.05). No filling related adverse reactions occurred in the three groups.【Conclusion】Hemostatic effect of vaseline gauze, AVF expansion hemostatic sponges and self-made flixonase collagen sponges to stop bleeding after chronic rhinosinusitis function endoscopic sinus surgery is similar, but the acesodyne effect of self-made flixonase collagen sponges is the most desirable. It is conducive to mucous epithelization of operative cavityand has the greatest clinical application value .
张雄. 慢性鼻-鼻窦炎功能性鼻内镜术后三种材料填充的止痛及止血效果比较[J]. 医学临床研究, 2018, 35(1): 30-33.
ZHANG Xiong. Comparison of Acesodyne and Hemostatic Effects of Three Filling Materials after Chronic Rhinosinusitis Function Endoscopic Sinus Surgery. JOURNAL OF CLINICAL RESEARCH, 2018, 35(1): 30-33.
2018, Vol. 35 
