Abstract：【Objective】To investigate the clinical efficacy of two kinds of nephron-sparing surgeries in the treatment of stage T1 renal carcinoma. 【Methods】The clinical data of 74 patients with stage T1a renal carcinoma treated by nephron-sparing surgery (NSS) in our hospital from January 2014 to December 2015 were retrospectively analyzed. According to the surgical method, the patients were divided into the laparoscopic group (40 cases) and laparotomy group (34 cases). The state of surgery and postoperative recovery, the incidence of complications and the positive rate of resection margin were compared between the two groups. The serum creatinine (SCr) level was determined, and the total glomerular filtration rates (GRF) of double kidneys were calculated. All patients were followed up for 7~28 months. The state of recurrence and metastasis in the two groups was recorded. 【Results】There was no significant difference between the two groups in postoperative drainage time and the positive rate of resection margin (P＞0.05). The surgical time and renal ischemia time of the laparoscopic group were longer than those of the laparotomy group, while the intraoperative blood loss and length of hospital stay were less and shorter than those of the laparotomy control group (P＜0.05). After surgery, GFR levels decreased in the two groups (P＜0.05), but there was no significant difference between the two groups (P＞0.05). The incidence of postoperative complications was lower in the laparoscopic group than in the laparotomy group (10.0% vs 29.41%) (χ2=4.515,P＜0.05). There was no recurrence or metastasis in the two groups. 【Conclusion】The tumor control effect of laparoscopic NSS and open NSS is similar. However, laparoscopic NSS can shorten the postoperative recovery time and reduce the incidence of postoperative complications. Though the time of renal ischemia is prolonged, renal damage is not aggravated.
顾硕,徐宗源. 两种保留肾单位术式治疗T1a期肾癌的临床疗效比较[J]. 医学临床研究, 2017, 34(8): 1518-1520.
GE Shuo, XU Zong-yuan. Clinical Efficacy of Two Kinds of Nephron-Sparing Surgeries in the Treatment of Stage T1 Renal Carcinoma. JOURNAL OF CLINICAL RESEARCH, 2017, 34(8): 1518-1520.
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