Abstract：【Objective】To investigate the effect of dexmedetomidine combined with sevoflurane on the circulatory indicators and recovery quality in pediatric hernia surgery. 【Methods】 Seventy-six children with hernia surgery were randomized into two groups, with 38 cases in each. The Dexmedetomidine group (A group) was treated with intravenous injection of dexmedetomidine 0.2 μg/(kg·h) by micro pump after tracheal intubation, while the control group (B group ) was treated with intravenous infusion of normal saline in the same dose. The operation time, recovery time, extubation time and agitation scores at 0 min and 30 min after entering the recovery room were compared between the two groups. Heart rate (HR) and mean arterial pressure (MAP) were recorded before operation (T 0), after anesthesia induction (T 1), 5min (T 2) and 10min (T 3) after the beginning of operation, and the end of operation (T 4). 【Results】 There were no significant differences between the two groups in terms of recovery time and extubation time (P＞0.05). At 0 min and 30min after entering the recovery room, the agitation scores of patients in A group were lower than those in B group (P＜0.05). Compared to T 0 , HR of A group was increased at T 1 and decreased at T 2 . From T 1 ~T 4 , HR of B group increased, and MAP increased at T 1 ~T 2 (P＜0.05). From T 1 ~T 4 , HR of A group was lower than of B group, and at T 2 ~T 3 , MAP was lower than that of B group (P＜0.05). The incidence rate of emergence agitation (EA) during the recovery period of general anaesthesia in A group was 7.89% which was lower than that in B group (39.47%) (P＜0.05). 【Conclusion】 Using dexmedetomidine combined with sevoflurane in pediatric hernia surgery not only can maintain hemodynamic stability during operation, but also can improve the recovery quality, and reduce the incidence rate of EA.
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2017, Vol. 34 
